For the treatment of osteoarthritis of the knee, are glucosamine and chondroitin as good as or better than NSAIDS for relief of pain?
Fineout-Overholt and Johnson (2005) provide examples of foreground clinical questions using PICO(T) format and types of evidence to answer the question:
| Foreground Clinical Questions | Types of Evidence to Answer the Question |
| Therapy: In patients living in a long-term care facility who are at risk for decubiti, what is the effect of an ongoing pressure ulcer prevention program compared to the standard of care (e.g., turning every two hours) on signs of emerging decubiti? | Randomized controlled trial (RCT) |
| Etiology: Are fair-skinned women who have prolonged unprotected UV ray exposure (>1 hour) at increased risk of melanoma compared to darker-skinned women without prolonged unprotected UV ray exposure? | Cohort Study |
| Diagnosis or diagnostic test: Is d-Dimer assay more accurate in diagnosing deep vein thrombosis compared to ultrasound? | RCT &/or Cohort Study |
| Prevention: For obese children does the use of community recreation activities reduce the risk of diabetes mellitus compared to educational programs on lifestyle changes over a 6-month period? | Prospective Study &/or RCT |
| Prognosis: Does dietary carbohydrate intake influence healthy weight maintenance (BMI less than 25) in patients who have family history of obesity (BMI greater than 30)? | Cohort Study &/or Case-Control Studies |
| Meaning: How do middle-aged women with fibromyalgia perceive loss of motor function? | Qualitative Study |
